منابع مشابه
Chance favors a prepared genome.
D uring evolution, all vertebrates have been exposed to multiple waves of crossspecies infection by retroviruses. A number of defensive strategies have developed, among them the spontaneous expression, throughout the body, of restriction factors, antiviral proteins that will bind to the capsid (CA) protein of incoming virions and interfere with virus replication (1). One example of such a prote...
متن کاملA Chance Favors a Prepared Mind: Chance Discovery from Cognitive Psychology
A chance has two contrary aspects: suddenness as an accidental finding and gradualness as the result of a prepared mind. Such duality of chance discovery resembles the insight process treated by problem solving researches. In this paper, we focus on the insight process in human problem solving, present a broad overview of its suddenness and the gradualness, and introduce our experimental result...
متن کاملReward Favors the Prepared
The dual mechanisms of control account suggests that cognitive control may be implemented through relatively proactive mechanisms in anticipation of stimulus onset, or through reactive mechanisms, triggered in response to changing stimulus demands. Reward incentives and task-informative cues (signaling the presence/absence of upcoming cognitive demand) have both been found to influence cognitiv...
متن کاملFortune Favors the Prepared
The intrinsic regenerative capacities of the adult mammalian heart are believed to be limited and insufficient to compensate for major cell loss upon injury. Transplantation of cells bearing regenerative potential emerged as a possible therapeutic strategy more than a decade ago; however, investigators continue searching for the ideal cell and implantation strategy. Mesenchymal stromal cells (M...
متن کاملChance favors the prepared mind--from serendipity to rational drug design.
Accidental discoveries always played an important role in science, especially in the search for new drugs. Several examples of serendipitous findings, leading to therapeutically useful drugs, are presented and discussed. Captopril, an antihypertensive Angiotensin-converting enzyme inhibitor, was the first drug that could be derived from a structural model of a protein. Dorzolamide, a Carboanhyd...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0800667105